THE ABSENCE OF CASPASE-8 IN THE DOPAMINERGIC SYSTEM LEADS TO MILD AUTISM-LIKE BEHAVIOR



Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation

Abstract Mutations in the Cockayne Syndrome group B (CSB) gene cause cancer in mice, but premature aging and severe neurodevelopmental defects in humans.CSB, Supplements a member of the SWI/SNF family of chromatin remodelers, plays diverse roles in regulating gene expression and transcription-coupled nucleotide excision repair (TC-NER); however, th

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